Rampage is a series of videogames released by Midway for various consoles. The basic premise of the series is that, due to a lab accident, the player controls a human transformed into a giant monster. The gameplay revolves around using your monster to destroy cities around the world while attacking or avoiding police and military forces.

The most recent Rampage game is the Wii version of Rampage: Total Destruction (which was released on November 19, 2006 (nearly nine months after the original Gamecube and PS2 video game release of the same name).

As of 2012, it is unknown whether or not there will be a sixth installment, a second spin-off, or anything in that matter. However, it has been announced that a theatrical film adaptation is under works at New Line Cinema.